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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC23IP
All Species:
14.55
Human Site:
Y223
Identified Species:
32
UniProt:
Q9Y6Y8
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6Y8
NP_009121.1
1000
111076
Y223
S
G
P
P
V
Q
M
Y
Q
M
P
P
G
S
L
Chimpanzee
Pan troglodytes
XP_508076
1000
111144
Y223
S
G
P
P
V
Q
M
Y
Q
M
P
P
G
S
L
Rhesus Macaque
Macaca mulatta
XP_001100615
1000
110977
Y223
S
G
P
P
V
Q
M
Y
Q
M
P
P
G
S
L
Dog
Lupus familis
XP_535037
1003
111786
Y223
P
G
P
P
V
Q
M
Y
Q
M
P
V
G
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6NZC7
998
110762
M221
P
P
V
Q
T
Y
Q
M
P
P
G
P
L
P
P
Rat
Rattus norvegicus
NP_001128331
999
110925
Q221
A
P
P
V
Q
T
Y
Q
M
P
P
G
P
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515025
1007
112022
P230
P
P
Q
G
Y
Q
T
P
P
G
S
L
P
L
I
Chicken
Gallus gallus
XP_424389
690
77700
S12
E
R
P
P
A
L
P
S
R
A
A
P
D
A
A
Frog
Xenopus laevis
NP_001087410
1007
112007
A222
F
Q
P
Q
G
L
P
A
S
L
P
P
P
P
R
Zebra Danio
Brachydanio rerio
NP_001070847
977
109367
P221
K
P
P
P
T
Q
I
P
P
P
P
P
T
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796242
926
103546
Q227
P
P
T
A
A
E
V
Q
Q
Q
T
Q
P
A
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
98.1
91.3
N.A.
86.3
88
N.A.
79.2
39.7
66.3
63.5
N.A.
N.A.
N.A.
N.A.
42.7
Protein Similarity:
100
99.3
98.8
93.4
N.A.
91.4
92.6
N.A.
86.3
51.5
76.4
74.9
N.A.
N.A.
N.A.
N.A.
56
P-Site Identity:
100
100
100
86.6
N.A.
6.6
13.3
N.A.
6.6
20
20
33.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
6.6
20
N.A.
13.3
33.3
26.6
46.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
19
0
0
10
0
10
10
0
0
19
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
37
0
10
10
0
0
0
0
10
10
10
37
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
19
0
0
0
10
0
10
10
19
37
% L
% Met:
0
0
0
0
0
0
37
10
10
37
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
37
46
73
55
0
0
19
19
28
28
64
64
37
19
28
% P
% Gln:
0
10
10
19
10
55
10
19
46
10
0
10
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
10
% R
% Ser:
28
0
0
0
0
0
0
10
10
0
10
0
0
37
10
% S
% Thr:
0
0
10
0
19
10
10
0
0
0
10
0
10
10
0
% T
% Val:
0
0
10
10
37
0
10
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
10
10
37
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _